The Lyssarians were a species in the Alpha/Beta Quadrant who had attained interstellar travel prior to 2153. The lead government of the Lyssarians was known as the Lyssarian Prime Conclave.

On the Lyssarian homeworld, there was a creature called a Lyssarian Desert Larvae. When it was injected with genetic material from another species, it created a mimetic simbiot, or a clone. The Lyssarian Prime Conclave deemed doing this illegal.

A rogue group who called themselves the Velandran Circle experimented with an enzyme which would slow the aging process of such a genetic clone. As of 2153, it was still experimental. (ENT: "Similitude")

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