Louise Samuels was the wife of William Samuels, a Human colonist on Volan II. Together they had two daughters, born in 2356 and 2358.

When her husband, a Maquis member, had died in Cardassian captivity, Starfleet attache to the DMZ, Calvin Hudson had to tell Louise about his death. (DS9: "The Maquis, Part I")

This character was only mentioned in dialogue.

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