Lissepia is a planet located in the Alpha Quadrant and homeworld to the Lissepian species.
During the 24th century, the Lissepians were active trade partners with the Cardassians. Lissepians were often employed as intermediaries between the Cardassians and their colonies in the Demilitarized Zone, following its creation in 2370. (DS9: "The Maquis, Part II")
In 2365, while the entire planet of Lissepia was celebrating Mother's Day, five thieves broke into the Central Bank of Lissepia and stole 1000 bricks of latinum in what became known as the "Lissepian Mother's Day Heist". Morn was one of five thieves who stole the 1000 bricks, later depositing the gold in the Bank of Bolias and storing the latinum in his second stomach. After the statute of limitations ran out in 2374, Morn faked his own death to throw his partners off from his trail. (DS9: "Who Mourns for Morn?")
In 2366, the Cardassian prison transport Ravinok was scheduled to rendezvous with another alien freighter, which would take Tora Naprem and Tora Ziyal to Lissepia to live out their lives in peace. The Cardassian transport, however, was attacked by two Breen warships and forced to crash-land on Dozaria, where the surivors remained until 2372. (DS9: "Indiscretion")