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Doctor Phlox was fond of leeches as a snack. In 2154, he snacked on some leeches while dictating a letter to Dr. Jeremy Lucas. He also fed one to a begging Porthos after warning him that it would clear out the dog's intestinal tract. (ENT: "Doctor's Orders")
The Emergency Medical Hologram of the USS Prometheus told The Doctor, after arriving in the Alpha Quadrant, that advances in medical equipment since the USS Voyager left meant that "scalpels and leeches" were not used anymore. (VOY: "Message in a Bottle")