A lair was the hiding place, cave, and shelter of an animal, including some mythological creatures.
In 2366, the Romulan defector Alidar Jarok called the crew of the USS Enterprise-D and the Federation a "lair of cowards" while being interrogated by Commander William T. Riker. (TNG: "The Defector")
According to Freya, the beast Grendel had a lair into which he dragged his victims. (VOY: "Heroes and Demons")
Garak spoke about the Dominion headquarter on Cardassia as their lair while trying to find a way to get inside. (DS9: "What You Leave Behind")
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