Kavis Alpha IV was the uninhabited fourth planet in its star system. This system was located in the Kavis Alpha sector.

In 2366, nanites threatened the USS Enterprise-D with destruction of its main computer core during an experiment in the system. After conflict with the crew of the Enterprise, and particularly the experiment's lead scientist Paul Stubbs, the nanites were relocated to Kavis Alpha IV, which Stubbs' influence had helped designate as their new home. The nanites left the Enterprise and began creating their own civilization on this planet. (TNG: "Evolution")

The Star Trek Encyclopedia (4th ed., vol. 1, p. 404) located this planet in Federation space.

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