Kareen lived and worked alone with Graves on the planet Gravesworld since her father died when she was very young. She was his personal assistant and cared for him during his terminal illness. In 2365, when Graves' illness caused his health to fall rapidly, she contacted the USS Enterprise-D.
Following Graves' death, he transferred his consciousness into Lieutenant Commander Data, becoming jealous when he saw any attention being given to Kareen. He had fallen in love with her, but there was too big an age difference between them. He offered to build an android for her mind, but this repulsed her. When he grabbed her while arguing with her, he fractured her left hand, as he was not used to Data's superior strength. Though her injuries were treated, Graves soon realized what he had lost and left Data's body shortly thereafter.