The Kalandra system was a star system in the Kalandra sector. It was known for its frequent ionic storms.

In 2375, during the Dominion War, the Federation Alliance was entrenched in the system and could move no further. In that year, Captain Benjamin Sisko and General Martok expressed their concerns that the ionic storms in the Kalandra system would expose the starships there to the Dominion, necessitating the need to expand the lines beyond it. (DS9: "The Emperor's New Cloak")

According to Star Trek: Star Charts (p. 47) and Stellar Cartography: The Starfleet Reference Library ("Federation Historical Highlights, 2161-2385"), this system was located in the Alpha Quadrant. The system's primary was a Class F star. It was the site of a battle prior to 2378.

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