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The Janeway Factor was an informal term used by Captain Braxton with regards to Captain Kathryn Janeway of USS Voyager. Braxton considered Janeway's meddling with the timeline a major annoyance, and coined the term to describe it. (VOY: "Relativity")
Braxton warned Seven of Nine to "watch out for the Janeway Factor." When Seven responded that she was not familiar with the protocol, he replied that her Captain had a knack for sticking her nose where it didn't belong, though Seven felt that Janeway could be a helpful resource. Braxton was not persuaded and ordered her directly to avoid contact with Janeway. (VOY: "Relativity")