The Irish Setter is a breed of domesticated dog, originating from Ireland, on Earth.
Q once turned Doctor Beverly Crusher into an Irish Setter when he grew impatient with her, Amanda Rogers turned her back into a human, however. (TNG: "True-Q")
In 2371, Captain Kathryn Janeway owned an Irish Setter named Molly which had puppies shortly after she left Earth to command the USS Voyager. (VOY: "Caretaker", "Hunters")
Q later tried to persuade Captain Janeway to mate with him by conjuring up a puppy. The female Q would later refer Janeway as "the dog." (VOY: "The Q and the Grey")
Beverly as an Irish Setter.
Molly, Janeway's Irish Setter.
An Irish Setter puppy.