Inaprovaline is a synaptic stimulant and cardiostimulant. Chloromydride is a stronger version of inaprovaline.
In 2151, while exploring an uncharted M-class planet, several of the crew of Enterprise became affected by tropolisine. Doctor Phlox discovered that inaprovaline, combined with being removed from the pollen-saturated environment, would allow the delusional effects of tropolisine to dissipate. (ENT: "Strange New World")
Also in 2151, while the crew of the Vahklas was aboard the Enterprise, T'Pol went to bed without meditating. Her dreams were unsettling and she was agitated upon awaking, so she asked Doctor Phlox for 25 milligrams of inaprovaline to calm her nerves. (ENT: "Fusion")
In 2366, the Zalkonian "John Doe" crash-landed on a planet and was rescued by the USS Enterprise-D. Suffering from low autonomic responses, Dr. Beverly Crusher gave "John Doe" sixty ccs of inaprovaline. (TNG: "Transfigurations")
When Worf began to lose brain function following his surgery involving the genitronic replicator in 2368, Dr. Beverly Crusher injected him with forty ccs of inaprovaline and then seventy-five ccs more. The drug did not have an effect, forcing her to try chloromydride. (TNG: "Ethics")
When Jean-Luc Picard was injured by a Lenarian at a diplomatic conference in 2369, Dr. Crusher injected him with forty ccs of inaprovaline. (TNG: "Tapestry")
Inaprovaline was administered to a patient in a field hospital on Ajilon Prime in 2373. (DS9: "Nor the Battle to the Strong")
In 2375, The Doctor administered 2 milligrams of inaprovaline to B'Elanna Torres to counter her cytotoxic shock. (VOY: "Nothing Human")
The same year, the Doctor gave twenty miligrams of inaprovaline to Captain Kathryn Janeway to cure her of her apparent space sickness. Unbeknownst to them, however, she was actually suffering from the early effects of temporal psychosis. (VOY: "Relativity")
- Although not mentioned in the episode, it is likely that The Doctor used inaprovaline to treat the other thirty-some crew members who came down with acute "space sickness" at the time. To quote The Doctor himself, "An injection a day keeps space sickness away. You try to be funny after treating thirty cases of nausea."
In Voyager's "Ashes to Ashes," Ensign Lyndsay Ballard is treated by Voyager's EMH with inaprovaline to help reverse the effects of genetic alterations performed by the Kobali, who had re-animated her lifeless corpse in accordance with their procreation customs. The injections prove to be ineffective in combating the pathogen responsible for her alteration. Changes from inaprovaline only affect Ensign Ballard's appearance, but not her genetic or psychological makeup.