A holographic research lab was a science laboratory equipped with holoemitters that allowed holographic testing of scientific hypotheses, ship designs, and other investigations. It appeared the same as a holodeck, with the exception of a control console in the center of the room.
- In 2373, the crew of the USS Voyager used the holographic research lab to extrapolate the evolution of the Hadrosaur if the species had not become extinct. (VOY: "Distant Origin")
- In 2376, Captain Janeway used the lab to make changes to the Michael Sullivan character in the Fair Haven program. (VOY: "Fair Haven")
- In 2377, B'Elanna Torres used the lab to extrapolate the appearance of her unborn child from certain changes made to the child's genome. (VOY: "Lineage")