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In 2374, after having detected the presence of the Omega molecule in the Delta Quadrant, Kathryn Janeway, captain of the USS Voyager, ordered Lieutenant Commander Tuvok and Ensign Harry Kim to outfit a photon torpedo with a gravimetric charge with a yield of fifty-four isotons, to create a gravimetric torpedo with which to destroy the molecule, in accordance with the highly-classified Omega Directive. When further investigation revealed that there may have been hundreds of Omega molecules, however, Janeway ordered the yield increased to eighty isotons. Eventually it was discovered that the amount of molecules was too great for even a torpedo to destroy, so Janeway had to resort to using a harmonic resonance chamber to destroy nearly fifty percent of the molecules, using the torpedo to destroy the rest. (VOY: "The Omega Directive")