Garanian bolites were tiny insects that had a peculiar effect on humanoids when they were brought into close contact with them.
In 2369, Nog and Jake Sisko played a trick on two Bajoran customers at the replimat. They put a small box with Garanian bolites next to their seats. After a little while, those Bajorans started to feel an itching sensation and their hands and faces first turned blue, then yellow, then green after which the sequence of colors repeated. However, a few seconds later, the effect of the Bolites ceased, and everything returned to normal. (DS9: "A Man Alone")
The scene featuring Jake and Nog's use of the Garanian bolites was originally to be featured in "Emissary" but, like other aspects of the pilot episode, were removed from the pilot's script and placed in the script of "A Man Alone" instead. (The Making of Star Trek: Deep Space Nine)
The script described the Bolites as "tiny alien critters".