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Spock, however, did not find any humor in breaking the Prime Directive, to which McCoy agreeably retorted "You could hardly claim to be an angel with those pointed ears, but say you landed someplace with a pitchfork", noting Spock's apparent physical similarities to the Devil. (TOS: "Bread and Circuses")
Leonardo da Vinci's painting Annunciation depicted Gabriel speaking to Mary. This painting was found among the relics in Kathryn Janeway's da Vinci holodeck program. (VOY: "Scorpion", "Scientific Method", "Concerning Flight", "The Raven")