A fracture (or bone fracture) is a medical condition in which there is a damage in the continuity of the bone.
In 2269, Hikaru Sulu suffered a compound fracture of his leg after being shrunk down to a small size and then falling from a console. He was treated for his injury by Doctor Leonard McCoy and Nurse Christine Chapel of the USS Enterprise. (TAS: "The Terratin Incident")
In 2344, Captain Rachel Garrett of the USS Enterprise-C was treated for serious injuries and a bad fracture after her vessel intervened in a Romulan attack on the Klingon outpost of Narendra III. During the attack, her vessel entered a temporal rift and was sent to an alternate version of 2366, where Captain Garrett's fracture was treated by Doctor Beverly Crusher of the USS Enterprise-D. (TNG: "Yesterday's Enterprise")
In 2369 Doctor Beverly Crusher treated Ishara Yar for a fracture. (TNG: "Legacy") Later that year, Captain Jean-Luc Picard of the USS Enterprise-D suffered a fracture of the arm following a shuttlecraft crash on Lambda Paz, a desert moon of Pentarus III. (TNG: "Final Mission")
In 2374, The Doctor, the EMH of the USS Voyager treated a female crewmember for a fractured vertebrae after she was injured Hirogen hunters who had taken over the vessel and forced the crew to be prey in various holodeck simulation. (VOY: "The Killing Game")