The Ferengi government was the government for the Ferengi Alliance, led by the Grand Nagus.

In 2369, the government had publicly expressed its doubts about the effectiveness of the metaphasic shield, which had been invented by the Ferengi citizen Doctor Reyga, in protecting a ship within a star's corona. Later that year, after Doctor Beverly Crusher performed an autopsy Reyga against the wishes of his family, Captain Jean-Luc Picard expressed his concerns about the significant repercussions of the Ferengi government getting involved when it learned that the burial rituals of one of its citizens had been violated. (TNG: "Suspicions")

In 2370, after Bok contacted the USS Enterprise-D, the Federation starship requested information about Bok from the government. However, a response to the request was delayed as the government was debating an amendment to the Rules of Acquisition. (TNG: "Bloodlines")