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In 2286, Doctor Gillian Taylor, a transplanted 20th century whale biologist, was assigned to a Federation science vessel shortly after her arrival to the 23rd century, in order to "catch-up on the past 300 years". (Star Trek IV: The Voyage Home)
In 2365, Captain Picard proposed requesting a Federation science vessel to their location in the Morgana Quadrant, to better study an unknown void discovered there by the USS Enterprise-D, prior to its entrapment in the phenomenon. (TNG: "Where Silence Has Lease")
In 2370, the Enterprise-D picked up a request for emergency assistance from a Federation science ship in the Topin system. This was a ploy devised by Ro Laren aboard a Maquis raider, to lure the Enterprise in so that she could steal a supply of medkits. (TNG: "Preemptive Strike")