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An exterminator was someone who eradicated non-sentient lifeforms, generally insects, from areas where they were unwanted.
Doctor Paul Stubbs likened nanites which had taken control of the USS Enterprise-D in 2366 to mosquitoes. Not believing that the nanites were sentient, he suggested that they be dealt with in the same manner as a "mosquito that bites your ear", with an exterminator. The eventual discovery of the nanites' sentience, however, precluded that possibility. (TNG: "Evolution")