Enterprise could refer to:
- The series Star Trek: Enterprise (originally just called Enterprise).
- One of the various vessels named Enterprise (see Enterprise history for more):
- HMS Enterprize, the British frigate
- Enterprise, the 19th century brig
- Any of the various ships bearing the name USS Enterprise
- Enterprise OV-101, the Space Shuttle
- Enterprise NX-01
- Mirror Universe Enterprises
- The notion of free enterprise.
- The following novels:
- Pocket Books' tie-in series Star Trek: Enterprise.
- "Enterprise: The First Adventure"
- My Brother's Keeper: Enterprise
- Star Trek: The Enterprise Logs, series of comics
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