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A counteragent was a type of drug that negated the effects of an illness or other drug.

Makara herbs were a counteragent for the sedatives Doctor Julian Bashir prescribed to Kira Nerys during her pregnancy in 2372. (DS9: "The Darkness and the Light")

The Doctor described the elusive, as-yet-unfound cure to Chakotay and Janeway's unknown disease as a counteragent. (VOY: "Resolutions")

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