A cortical analeptic was a type of drug administered via hypospray, used to reinvigorate tissue in the cerebral cortex.

In 2371, Julian Bashir gave Jadzia Dax several cortical analeptics after Dax was attacked by a Changeling aboard the USS Defiant and had suffered a concussion in the attack. (DS9: "The Adversary")

The Doctor had Kes prepare several doses of the drug while he prepared to perform motor cortex reconstruction surgery on Tom Paris in 2373. (VOY: "The Swarm")

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