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Cold Station 12, also known as C-12, was a top-secret facility located in an asteroid in the 22nd century. It was jointly operated and staffed by Humans and the Denobulans under the auspices of the Interspecies Medical Exchange. The facility was used to store hazardous viruses and pathogens for research purposes, as well as over 1,800 embryos of 20th century Augments, left over from the Eugenics Wars.
Nineteen of the Augment embryos were stolen in the 2130s by facility chief of staff Doctor Arik Soong. Soong intended to create a new race of "supermen" and took the embryos to the Trialas system, where he raised them as his children. In 2154, Doctor Jeremy Lucas became the facility's chief of staff. Soong returned to C-12 in May of that year in a stolen Klingon Bird-of-Prey, along with his "children," to take the remaining embryos. Enterprise NX-01 arrived in an attempt to stop Soong, forcing him to take hostages. Malik, one of the Augments, brutally interrogated Dr. Lucas, and even killed one of his staff members using Symbalene blood burn, in an attempt to extract the access code that would grant them access to the rest of the Augment embryos.
Captain Archer led a boarding party to C-12 in an attempt to stop Soong, but they were soon taken prisoner as well. When Malik threatened to kill Doctor Phlox, Lucas' old friend, Lucas relented and input the access code, granting Soong access to the embryos. Enterprise attempted to destroy the station rather than let Soong escape with the embryos, but Soong and the Augments were able to escape aboard the Bird-of-Prey. Before they left, however, Malik set the stasis fields containing the pathogens in the station to collapse, hoping to kill everyone aboard. Fortunately, Captain Archer was able to reroute the power relays and protect the main core of the station. Afterward, Doctor Lucas and his staff remained behind to begin decontamination procedures, which Lucas estimated would take a year. (ENT: "Cold Station 12", "The Augments")