The Cochrane family was a notable Human family in the mid-22nd century that was descended from Doctor Zefram Cochrane, the creator of warp drive on Earth.

In October 2152, after the discovery of a small pod, Dr. Phlox submitted a request to Dr. Cochrane's family in order for them to release Cochrane's genetic profile. (ENT: "Future Tense") At the time, it was believed that the pod's deceased pilot may have been Dr. Cochrane, who had left his home in the Alpha Centauri colony for an unknown destination in 2119 and was later presumed dead. (TOS: "Metamorphosis") The family transmitted Cochrane's profile to Enterprise, shortly thereafter. (ENT: "Future Tense")

At one point, Brannon Braga speculated that the Cochrane family was probably killed in World War Three. ("The Legacy of Zefram Cochrane" documentary featurette, Star Trek: First Contact Special Edition/Blu-ray) It is possible that the family lived near Alpha Centauri, which is where Cochrane is stated to be from in TOS: "Metamorphosis".