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The Cochrane Equation was a fundamental mathematical expression in warp theory related to the creation of a stable warp field within the laws of physics. The equation was named after Zefram Cochrane, who wrote the book on warp theory on Earth.
In 2153, Enterprise NX-01 entered the Delphic Expanse and encountered spatial anomalies which were a characteristic of the region. Commander Tucker noted that inside these areas of extreme spatial distortion, the Cochrane Equation was no longer a constant. Within the anomalies, the quantum variables became a problem for establishing a stable warp field. Any attempt to compensate caused problems with the spatial gradients. Tucker noted he could have used help from Isaac Newton to solve the problem.