A rag dipped in chloroform

Chloroform was a drug which could be used as a sedative on Humans.

In 2004, Loomis used a chloroform-covered rag to render Georgia Tandy unconscious. She was thus sedated in preparation for Loomis taking her to be medically experimented on by Xindi-Reptilians who were endeavoring to create a bio-weapon. (ENT: "Carpenter Street")

Though chloroform is shown being used only in the kidnapping of Georgia Tandy, the drug presumably was additionally used by Loomis to render other Humans unconscious, such as Lawrence Strode.

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