Chloe O'Shannon was a Human child in the fourth grade in the year 2151. A student in Miss Malvin's class at the Worley Elementary School in Kenmare, County Kerry, Ireland on Earth, Chloe sent questions, letters, and drawings to Enterprise NX-01.

Chloe's question was "How do we talk to aliens?" and one of the few that was answered personally. Captain Archer delegated answering the question to communications officer Hoshi Sato. Ensign Sato explained the purpose and function of the universal translator. She also explained proper procedures when the translator was unable to make a fix on an unknown language. (ENT: "Breaking the Ice")

This character was only mentioned in dialogue.