The Chamber of Opportunity was where the Grand Nagus of the Ferengi Alliance oversaw all financial prospects from his throne.

In 2374, Ishka commented that one day a female would climb the 42 flights of stairs to the Chamber of Opportunity and take her rightful place as Grand Nagus. Quark also once visited Grand Nagus Zek in the Chamber of Opportunity while on Ferenginar. (DS9: "Profit and Lace", "Ferengi Love Songs")