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Cardiomyopathy ("heart muscle disease") is the deterioration of the function of the myocardium (the actual heart muscle) for any reason. People with cardiomyopathy are often at risk of arrhythmia or sudden cardiac death, or both.

Ralph Offenhouse, a Human rescued by the USS Enterprise-D in 2364, originally died of the condition, but was revived and cured of it after his body was recovered in a cryogenically frozen state. (TNG: "The Neutral Zone")

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