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In 2376, Commander Peter Harkins' wife Angie had a sister from Boston that was visiting San Francisco; Harkins suggested to coworker Lieutenant Reginald Barclay that he may like to meet her. (VOY: "Pathfinder")
In Dangerous Ground, Doctor John Rawley left Fairbridge, Berkshire County, to attend a state medical convention in Boston. After the convention ended, the doctor returned to Fairbridge. (TNG: "The Big Goodbye")