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Bio-neural circuitry is a technology incorporated in bio-neural gel packs. It was incorporated into Federation Starship USS Voyager around 2371. Much of the usual isolinear circuitry was replaced with bio-neural cells, which can process information more efficiently, and hence speed up computer response time. The Intrepid-class was the first equipped with bio-neural systems. (VOY: "Caretaker")
Bio-neural technology can be affected by viruses and other infectious agents, which compromise healthy tissue of living organisms. When the bio-neural gel packs aboard Voyager were infected, The Doctor suggested inducing fever in order to fight the infection, similar to when a Human sometimes has a fever in response to infection and illness. B'Elanna Torres used an inverted warp field to superheat the vessel and kill the bacteria infecting the bio-neural circuits. As a result of this problem and Voyager's inability to procure replacement gel packs, attempts were made to replace those systems reliant on bio-neural circuitry with more conventional technology. (VOY: "Learning Curve")
The Vidiian Danara Pel was found to have a parietal lobe implant consisting of nanofibers in a complex web of bio-neural circuitry. The Doctor used the synaptic patterns stored in this circuitry to create a holographic projection of Denara. (VOY: "Lifesigns")