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The planet Omicron Ceti III was bombarded in berthold rays, but unfortunately the rays were not known to Federation science until 2267, after a few colonies had already been established on the planet and wiped out under unknown circumstances. The last colony, the Omicron colony of 2264, was protected by spores. The colony had to be relocated because living animal matter could only survive on Omicron Ceti III for a week without protection. (TOS: "This Side of Paradise")