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Barclay's Protomorphosis Syndrome

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Lieutenant Worf after being devolved by Barclay's Protomorphosis Syndrome

Troi de-evolved

Counselor Troi after being devolved by Barclay's Protomorphosis Syndrome

Reginald Barclay devolved

Lieutenant Barclay after being devolved by Barclay's Protomorphosis Syndrome

Barclay's Protomorphosis Syndrome was an artificial disease, accidentally created by Dr. Beverly Crusher aboard the USS Enterprise-D in 2370. Attempting to cure Lieutenant Reginald Barclay of Urodelan flu, Dr. Crusher used synthetic T-cells to activate the gene that would fight off the infection. However, an anomaly in Barclay's genetic structure caused the T-cell to mutate and activate all of Barclay's dormant genes, including his latent introns. Interaction with the Urodelan virus caused the T-cells to become airborne, spreading throughout the ship and causing the crew to "de-evolve." The syndrome was cured by using amniotic fluid to create a retrovirus, eliminating the effects.

Initial symptoms of the disease include abnormal behavior, irritability, hyper-activity or decreased activity, chills, fever and paranoia.

Ultimately, the newly active genes aggressively express themselves, drastically altering the body and causing the suffering patient to physically regress into an earlier form of his or her respective species, or possibly even a combined form of multiple animal types. (TNG: "Genesis")

List of victims

Though every lifeform aboard the Enterprise-D was affected, the following is a list of people actually shown to have been affected:

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