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An antibiotic was a chemotherapeutic drug used to inhibit or abolish microorganisms, such as bacteria, fungi, or protozoa.

In late 2000, Shannon O'Donnell called the nonexistence of antibiotics one downside of the classical age, but Henry Janeway replied that this had caused families to care for each other. (VOY: "11:59")

In early 2375, Doctor Julian Bashir was to give Quark an antibiotic for an ear infection. (DS9: "Afterimage")

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