The Antares maelstrom was a powerful and destructive astronomical phenomenon.

In 2285, Khan, during his mission of vengeance against James Kirk, swore he would chase Kirk "'round the moons of Nibia and 'round the Antares maelstrom and 'round perdition's flames" before giving up. (Star Trek II: The Wrath of Khan)

This astronomical object was only mentioned in dialogue.
The quote is paraphrased from Moby Dick, in which Ahab merely vows to follow the titular whale round the Norway Maelstrom instead.

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