(covers information from several alternate timelines)
A week after she came aboard, in late 2373, the Defiant entered the atmosphere of a planet (later named "Gaia") and discovered a settlement of the crew's descendants from an alternate timeline. In the alternate timeline, the crew of the Defiant were sent back in time 200 years, and marooned on the planet.
In this timeline, Angie Kirby and Doctor Bashir married and procreated, leaving the planet "crawling with Bashirs" by the time the Defiant made its visit. Upon learning of this fact, Bashir was confused, as he'd never met the woman prior to discovering their descendants. When the Defiant failed to go back in time and fulfill its supposed "destiny", the colony (and therefore their descendants) presumably ceased to exist. (DS9: "Children of Time")
In 2374, she participated in an attack on a Dominion sensor array in the Argolis Cluster. Afterward, she found it difficult to believe that Julian Bashir had helmed the Defiant after Lieutenant Haj had been injured. (DS9: "Behind the Lines")