22nd century

The 22nd century, defined in the calendar of Earth as the period from 2101 to 2200, was a period of significant change, first for Earth, and then other species as well. In the early part of the century, Earth made the first steps toward a planetary government and prosperous society. The mid-century was a particularly eventful time, with the launch of Earth's first starship capable of warp 5 and man's first forays into deep space, the Xindi attack on Earth, and the Earth-Romulan War. Contacts and alliances made in the 2150s paved the way for the founding of the United Federation of Planets in 2161. (I AM ERROR)

Decades

2100s • 2110s • 2120s • 2130s • 2140s • 2150s • 2160s • 2170s • 2180s • 2190s

Major events

2103: The Martian colonies are established. (VOY: "Lifesigns", "The 37's")
2105: Eight women are knifed to death in the Martian colonies by the entity later known as Redjac. (TOS: "Wolf in the Fold")
2113: By this year, war, poverty, disease, and hunger have been virtually eliminated on Earth. (Star Trek: First Contact, ENT: "Broken Bow")
2123: SS Mariposa, a DY-500 class ship, is launched from Earth on a mission of colonization to the Ficus sector on 27 November. (TNG: "Up The Long Ladder")
2143: Humans break the warp 2 barrier as part of the Warp Five and NX Programs. (ENT: "First Flight")
2150: Earth becomes fully unified when all nation-states join the World Government, completing a process initiated earlier in the century by the European Hegemony. (TNG: "Attached", "Up The Long Ladder")
2151: As a result of its successful Warp Five program, Earth launches Enterprise NX-01, leading to numerous decisive first contacts over the coming years. (I AM ERROR)
2153: Lasting almost one year, the Xindi crisis begins with an attack on Earth costing the lives of seven million people. (ENT: "The Expanse", "Zero Hour", "Home")
2154: On Vulcan, the Romulan-influenced government is overthrown by the Syrrannites. Vulcan, together with forces from Earth, Andoria, and Tellar, jointly resolves the Babel Crisis shortly after. (ENT: "Kir'Shara", "United")
2155: Human, Vulcan, Andorian, Tellarite, and other representatives hold a conference on forming a Coalition of Planets. (ENT: "Demons", "Terra Prime")
2161: After jointly winning a war against the Romulans lasting from 2156 to 2160, Earth, Vulcan, Andoria, and Tellar found the United Federation of Planets in San Francisco. (ENT: "Zero Hour", "These Are the Voyages..."; TNG: "The Outcast")
2164: The USS Franklin vanishes while on a mission in the Gagarin Radiation Belt. (Star Trek Beyond)
2167: The USS Essex is lost after visiting a moon of Mab-Bu VI. (TNG: "Power Play")
2184: Jonathan Archer begins an eight-year tenure as President of the United Federation of Planets. (ENT: "In a Mirror, Darkly, Part II")

Mirror universe

January 2155: Jonathan Archer, and then Hoshi Sato, launch a coup against the Terran Empire on board the USS Defiant. (ENT: "In a Mirror, Darkly, Part II")

Events without specified years

Early 22nd century

A loose alliance known as the European Hegemony is formed on Earth, representing the first stirrings of what will eventually become a world government. (TNG: "Up The Long Ladder")
Amid the chaos of Earth's ongoing recovery from World War III, philosopher Liam Dieghan founds the Neo-Transcendentalist movement, advocating living simply and in harmony with nature. (TNG: "Up The Long Ladder")
An era of stability for the Alpha Quadrant comes to an end. It won't see the same level of stability until the Klingon-Federation alliance is formed 200 years later. (VOY: "Alliances")

Late 22nd century

The white rhinoceros becomes extinct on Earth. (TNG: "New Ground")
The New World Economy takes shape in the Federation, and money becomes obsolete. (VOY: "Dark Frontier")
With his lightship, Akorem Laan enters the Bajoran wormhole, where he would stay with the Prophets until 2372. (DS9: "Accession")
In an alternate timeline, the Defiant crash lands on Gaia. The ship's crew colonizes the planet. (DS9: "Children of Time")

Unspecified

The Quadros-1 probe is launched by the Federation. (DS9: "Emissary")
Berlinghoff Rasmussen lives in this century, until he steals a time-pod from a 26th century-time traveler and leaves for the year 2368, where he claims to have once gone back in time and visited a 22nd century vessel with a colleague. (TNG: "A Matter of Time")
A Bajoran ship carrying Kai Taluno is disabled in the Denorios belt. (DS9: "Emissary")
The 27th century inventor and scientist Kal Dano hides his invention, the Tox Uthat, on the planet Risa. (TNG: "Captain's Holiday")
On Cardassia Prime, burial vaults of the First Hebitian civilization are unearthed for the first time. They are plundered by impoverished Cardassians, and most of the artifacts are stolen. (TNG: "Chain of Command, Part II")
Guinan has "some dealings" with Q. (TNG: "Q Who")
An ancestor of Elizabeth Dehner is noted for having an aptitude for extra-sensory perception. (TOS: "Where No Man Has Gone Before")
As punishment for their resistance, the Dominion infects the Teplans with the Blight. (DS9: "The Quickening")
Progeria, a genetic disease occurring very rarely among Human children, is eradicated. (VOY: "Scientific Method")
Laas begins living with the Varalans. (DS9: "Chimera")
Giuseppina Pentangeli is active as a soprano, later regarded to be the greatest of this century. (VOY: "The Swarm")
Fortune cookies stop being the family business of Gabriel Lorca's ancestors. (DIS: "Context Is for Kings")
Michael Eddington's family acquires a looney which Eddington will later possess and consider lucky. (DS9: "Blaze of Glory")
The Genome colony on Moab IV is founded. (TNG: "The Masterpiece Society")
Deneva is colonized by Humans. (TOS: "Operation -- Annihilate!")