- One of the Human males examined by Dr. McCoy in the Omicron colony was born in this year. (TOS: "This Side of Paradise")
- Straal and Paul Stamets begin working together. (DIS: "Context Is for Kings")
- Doctor Elizabeth Dehner's medical records viewed in 2265 give Dehner's age as 21, suggesting she was born in 2244. However, it is unclear whether those records were up-to-date or whether they were from her last medical examination. In any event, she was born in the city of Delman. (TOS: "Where No Man Has Gone Before")
- The Star Trek Encyclopedia (4th ed., vol. 1, A-L, p. 349) places the event of James T. Kirk crashing his stepfather's Corvette in this year.