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- Briam of Krios Prime is born. (TNG: "The Perfect Mate")
- The starship Horizon visits Sigma Iotia II, a planet that was home to a pre-warp society. One of the ship's crew members accidentally leaves behind a book, Chicago Mobs of the Twenties. The Horizon is lost shortly after leaving the planet, but transmits a radio frequency distress call that will not be received by Starfleet until almost a hundred years later. (TOS: "A Piece of the Action")
- The white rhinoceros becomes extinct on Earth. (TNG: "New Ground")
- The Genome colony on Moab IV is founded. (TNG: "The Masterpiece Society")
- "A Piece of the Action" implies that the Prime Directive was not in force at this time.