- Humanity unofficially makes first contact with the Klingon Empire when Klaang crash-lands in Broken Bow, Oklahoma. (ENT: "Broken Bow")
- Earth Starfleet launches Enterprise NX-01, its first starship to use the warp five engine, opening up a new age of exploration for Earth. Enterprise also begins Humanity's involvement in the Temporal Cold War with the first encounter with the Suliban Cabal. (ENT: "Broken Bow")
- The Andorians destroy the facility on P'Jem, though they give sufficient warning for personnel present to evacuate first. (ENT: "Shadows of P'Jem")
- The Paraagan colony on Paraagan II was visited by outsiders. The foreman of the colony would later inform T'Pol of this fact during the Enterprise NX-01's visit to the planet six months later. (ENT: "Shockwave")
- Other Earth first contacts this year include the Akaalis, the Axanar, the Coridans, the Eska, the Kantare, the Malurians, the Menk, the Valakians, and the Xyrillians. (ENT Season 1)
- Trip Tucker experiences the first inter-species pregnancy involving a Human, at least to Jonathan Archer, Phlox, and Tucker's knowledge. (ENT: "Unexpected")
This article might be inaccurate This page has been identified as needing attention. Please visit the article's talk page to see what needs fixing and feel free to edit this page to assist with this task.