- By this year, the post-atomic horror is underway on Earth with all "United Earth nonsense" being abolished and the New United Nations having ceased to exist. (TNG: "Encounter at Farpoint"; ENT: "In a Mirror, Darkly, Part II")
- In this year, the number of stars on the United States of America flag changes from the 52 displayed since 2033. (TNG: "The Royale")
- The Earth era known as AD is still in effect as of this year. (TNG: "The Royale")
- According to the Star Trek: Star Charts (p. 64) and the Stellar Cartography: The Starfleet Reference Library ("Federation Historical Highlights, 2161-2385"), the S.S. Bonaventure was lost in the Delta Triangle.